Xue Cai

Research Assistant

ORCID: 0000-0002-7427-2100

Xue received training of analytical chemistry (2011-2018) in Zhejiang University of Technology, majoring in chromatography and mass spectrometry. In 2017, she published an article entitled comparing the fragmentation reactions of protonated cyclic indolyl α-amino esters in Q/Orbitrap and QTOF mass spectrometers in Rapid Communications in Mass Spectrometry. At school, Xue won “WYNCA” Enterprise Scholarships once, School-level first-class scholarships twice, Social Work Award twice, Excellent Graduate Student Cadre once, Excellent League cadres twice. In April 2018, Xue joined guomics lab as a research assistant. In January 2020, Xue won the award for outstanding performance of Westlake University in 2019.


Publication list

1.Meng Xu*, Jingwen Deng*, Kaikun Xu*, Tiansheng Zhu*, Ling Han, Wang Dan, Yaoting Sun, Cheng Chang, Xiaomei Zhang, Jiayu Dai, Liang Yue, Qiushi Zhang, Xue Cai, Yi Zhu, Hu Duan, Yuan Liu, Dong Li, Yunping Zhu, Timothy R. D. J. Radstake, Deepak M.W. Balak, Danke Xu*, Tiannan Guo#, Chuanjian Lu# and Xiaobo Yu#. In-depth Serum Proteomics Reveals Biomarkers of Psoriasis Severity and Response to Traditional Chinese Medicine. Online in Theranostics.
2. Cao X, Cai X, Mo W. Comparing the fragmentation reactions of protonated cyclic indolyl α-amino esters in quadrupole/orbitrap and quadrupole time-of-flight mass spectrometersRapid Commun Mass Spectrom. 2018 Apr 15;32(7):543-551. doi: 10.1002/rcm.8063.
3. Fangfei Zhang, Weigang Ge, Guan Ruan, XueCai, Tiannan Guo *. Data-Independent Acquisition Mass Spectrometry andSoftware Tools: a Review in 2020. Proteomics. Invited review. In revision.   This paper reviews the history and state ofthe art of DIA-MS and software tools.
4. Cai, Xue;Ge, Weigang; Yi, Xiao; Sun, Rui; Zhu, Jiang; Lu, Cong; Sun, Ping; Zhu,Tiansheng; Yuan, Chunhui; Ruan, Guan; Liang, Shuang; Lv, Mengge; Huang, Shiang;Zhu, Yi *; Guo, Tiannan *. PulseDIA: in-depth data independent acquisition massspectrometry using enhanced gas phase fractionation.https://www.biorxiv.org/content/10.1101/787705v1.   In revision. This paper reports a patentedtechnology to improve DIA sensitivity using gas phase fractionation.
5. Rui Sun #, Christie Hunter *#, Chen Chen,Weigang Ge, Nick Morrice, Qiushi Zhang, Xue Cai, Bo Wang, Xiaoyan Yu,Xiaodong Teng, Lirong Chen, Shaozheng Dai, Jian Song, Zhongzhi Luan, ChangbinYu, Ruedi Aebersold, Yi Zhu *, Tiannan Guo *. Accelerated Protein BiomarkerDiscovery from FFPE tissue samples using Single-shot, Short Gradient MicroflowSWATH MS. (http://biorxiv.org/cgi/content/short/675348v1).   Journal of Proteome Research. 2020.Accepted.   This paper developed andevaluated a 15-min microflow-SWATH method for improve throughput.
6. Xi Zheng#, Kailun Xu#, Yingkuan Shao#,Biting Zhou, Ting Chen, Yanqin Huang,Qilong Li, Fei Wen, Weiting Ge, Jian Wang,Shaojun Yu, Liang Zhu, Liang Yue, Xue Cai, Qiushi Zhang, Guan Ruan,Tiansheng Zhu, Zhicheng Wu, Yi Zhu, Tiannan Guo*,Shu Zheng*. A circulatingexosomes-based novel screening tool for colorectal cancer revealed by Shotgunand Data Independent Acquisition mass spectrometry. In revision.   This paper reports development of aexosome-based biomarker for CRC.
7. Tiansheng Zhu #, Yi Zhu #*, Yue Xuan #,Huanhuan Gao, Xue Cai, Sander R. Piersma, Thang V. Pham, TimSchelfhorst, Irene Bijnsdorp, Rui Sun, Liang Yue, Guan Ruan, Qiushi Zhang, MoHu, Yue Zhou, Winan J. Van Houdt, T.Y.S Lelarge, J. Cloos, Anna Wojtuszkiewicz,Danijela Koppers-Lalic, F. Böttger, Chantal Scheepbouwer, R.H Brakenhoff, G.J.L.H.van Leenders, Jan N.M. Ijzermans, J.W.M. Martens, R.D.M. Steenbergen, N.C.Grieken, Sathiyamoorthy Selvarajan, Sangeeta Mantoo, Sze Sing Lee, Serene JieYi Yeow, Syed Muhammad Fahmy Alkaff, Nan Xiang, Yaoting Sun, Xiao Yi, ShaozhengDai, Wei Liu, Tian Lu, Zhicheng Wu, Xiao Liang, Man Wang, Yingkuan Shao, XiZheng, Kailun Xu, Qin Yang, Yifan Meng, Cong Lu, Jiang Zhu, Jin’e Zheng, BoWang, Sai Lou, Yibei Dai, Chao Xu, Chenhuan Yu, Huazhong Ying, Tony Kiat-honLim, Jianmin Wu, Xiaofei Gao, Zhongzhi Luan, Xiaodong Teng, Peng Wu, Shi’angHuang, Zhihua Tao, N. Gopalakrishna Iyer, Shuigeng Zhou, Wenguang Shao, HenryLam, Ding Ma, Jiafu Ji , Oi Lian Kon, Shu Zheng, Ruedi Aebersold, Connie R.Jimenez, Tiannan Guo *. DPHL: A pan-human protein mass spectrometry library forrobust biomarker discovery. Genomics, Proteomics and Bioinformatics.(Accepted). This paper reports the most comprehensive human tissue DIA libraryfrom over 1000 DDA analysis from 16 human tissue types collected from over 20clinical centers.   (Initial version inBioRxiv: https://www.biorxiv.org/content/10.1101/2020.02.03.931329v1)


Email: caixue AT westlake.edu.cn